Samarth IVF Oocyte & Embryo Donation Program

Understanding Oocyte and Embryo Donation: A Path to Parenthood

Is Oocyte Donation for You?

Oocyte donation becomes an invaluable option in the following scenarios:

Premature Ovarian Failure:

When the ovaries lose their function prematurely.

Ovarian Agenesis or Dysgenesis:

A condition characterized by the absence or underdevelopment of the ovaries.

Iatrogenic Causes:

These may arise due to oophorectomy (removal of ovaries) or chemical castration.

Poor Responders to Ovulation Induction:

For those who do not respond well to standard ovulation induction treatments.

Carrier of Autosomal Recessive Disorders:

In situations where the recipient is a carrier of inheritable genetic diseases.

Peering into the Procedure

The journey of oocyte donation unfolds in two main phases:

Evaluation of Oocyte Donor:

A potential oocyte donor undergoes thorough scrutiny, which includes:

• Age between 21 and 36 years, ensuring optimal reproductive health.
• A detailed assessment of personal and sexual history.
• A battery of serological tests, covering syphilis, HIV, HbsAg, HCV, and CMV antibodies.
• Genetic screening for autosomal dominant and recessive disorders.
• Transvaginal ultrasound to monitor ovulation patterns.

Evaluation of Oocyte Recipient:

The recipient’s journey begins with:

• A comprehensive evaluation of medical and reproductive history, complemented by a physical examination.
• Essential serological tests.
• Assessment of endometrial receptivity, a vital element ensuring a harmonious union between embryo transfer and the uterine environment.

Synchrony between embryo transfer and endometrial receptivity is vital.

It’s achieved through various approaches:

• Women with functioning ovaries are down regulated with GnRH agonists.
• Those facing ovarian failure undergo no down regulation.
• Exogenous hormone replacement, simulating a natural cycle, is used to optimise uterine receptivity.